Corning® 50L DMEM (Dulbecco’s Modified Eagle’s Medium), Powder (50-003-PC)

[+] 4.5 g/L glucose, L-glutamine, sodium pyruvate[-] sodium bicarbonate Technical Advantage: Substitution of Pyridoxine HCl for Pyridoxal ensures improved stability over the original formulation Dulbecco's Modified Eagle's Medium (DMEM) is a modification of Basal Medium Eagle (BME) containing four-fold concentrations of the amino acids and vitamins found in BME. The original formulation was used to culture embryonic mouse cells and has since been modified to support a variety of normal and transformed cells, such as primary cultures of mouse and chicken cells. DMEM formulations can differ in the amount or absence of components such as glucose, sodium pyruvate, sodium bicarbonate and L-glutamine. DMEM 50-003-PB and -PC contain 4.5 g/L glucose, L-glutamine, and sodium pyruvate and are formulated without sodium bicarbonate. The original formulation contained 1000 mg/L of glucose and was used to culture embryonic mouse cells. Since then, it has been modified to support primary cultures of mouse and chicken cells, as well as a variety of normal and transformed cells.