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| Artikel-Nr.: 5667A-9783030007362 Herst.-Nr.: 9783030007362 EAN/GTIN: 9783030007362 |
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![](/p.gif) | This book reviews recent work on molecular chaperones of the prefoldin family from their discovery in Archaea to the basic clarification of their structure. Even though, there is still a lot to investigate in order to understand the roles and functions of prefoldins, some preliminary work suggests their contribution in assembly and activation of a variety of macromolecular complexes. Hence, the reader is introduced to recent structural findings via cryo-electron microscopy and to the importance of this particular group of proteins in health and disease. This book also discusses the particular structure of the URI prefoldin-like complex. In addition, recent developments in the generation of URI mouse models speculate on the functions and emerging roles of the URI prefoldin-like complex in various cellular processes. This novel protein complex represents a unique cellular machinery, which molecular basis of its activity still remains to be determined. Weitere Informationen: ![](/p.gif) | ![](/p.gif) | Author: | Nabil Djouder | Verlag: | Springer International Publishing | Sprache: | eng |
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![](/p.gif) | Weitere Suchbegriffe: Biochemie, Chemie / Biochemie, Forschung (medizinisch, psychologisch), Genetik / Humangenetik, Humangenetik, Heilkunde, Humanmedizin, Medizin, Medizin / Spezialgebiete, Biologie / Molekularbiologie, Molekularbiologie |
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