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| Artikel-Nr.: 5667A-9783030638160 Herst.-Nr.: 9783030638160 EAN/GTIN: 9783030638160 |
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![](/p.gif) | This book reviews collagen-based biomaterials that have been applied broadly to tissue engineering and local drug delivery applications and lays out a landscape for developing a multifunctional biograft material from collagen polymers. The book also discusses current shortcomings in collagen based drug delivery opportunities, including poor mechanical properties, rapid proteolytic degradation, and cursory control over physical properties and molecular release profiles. Finally, a review of application of the collagen biograft materials for promoting neovascularization and tissue regeneration is presented, using examples of established in-vivo chicken egg chorioallantoic membrane (CAM) model. Use of heparin for affinity-based vascular endothelial growth factor (VEGF) retention in collagen constructs is also discussed for promoting neovascularization. Weitere Informationen: ![](/p.gif) | ![](/p.gif) | Author: | Rucha Joshi | Verlag: | Springer International Publishing | Sprache: | eng |
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![](/p.gif) | Weitere Suchbegriffe: Collagen-based drug delivery, Collagen polymers for tissue engineering, Self-assembling polymer, Collagen biografts, Wound healing, Neovascularization, Vascularization, Blood vessel formation, Chicken egg chorioallontoic membrane assay (CAM), Heparin, Affinity based drug retention |
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