Heparin. New biochemical and medical aspects

Frontmatter -- Preface -- Introductory Welcome -- List Of Participants -- Contents -- I. Heparin: Structure, Mechanism of Action, Biosynthesis and Catabolism -- The Function and Structure of the Heparin Molecule / Rosenberg, Robert D. -- Biosynthesis of Heparin / Riesenfeld, Johan -- Physiological Heparin - its Function and Fate / Dawes, Joan -- Mechanism of Heparin Rebound and Heparin-Protamine Interactions / Aronson, Moshe / Fabian, Ina / Bleiberg, Ilan -- II. Methods for the Determination of Heparin -- Overview on Methods for the Determination of Heparin / Witt, Irene -- Control of Heparin Therapy by Measurement of the Antithrombin III-Heparin-Complex / Lill, Helmut -- Determination of Heparin by a Fluorogenic Synthetic Substrate / Spaethe, Reiner / Naumann, Margot / Strauß, Joan -- Properties of the Coatest ® Heparin As say / Friberger, Petter -- A Sensitive Competitive Binding Assay for Heparin / Dawes, Joan -- Determination of Low Dose Heparin Activities in Plasma / Róka, Ladislaus -- Characterization of Heparin Preparations in Vivo by Different Test Systems / Harenberg, Job / Fussi, Fernando / Junker, Werner / Mattes, Kurt / Weber, Ellen / Zimmermann, Rainer -- Determination of Heparin and Fractionated Heparin with Different Molecular Weights / Schmitz-Huebner, Ulrich -- III. Clinical Usage of Heparin -- Low Molecular Weight Heparin and the Prevention of Postoperative Deep Vein Thrombosis / Kakkar, V. V. / Djazaeri, B. / Fok, J. / Scully, M. / Westwick, J. -- The Effect of Heparins on Platelet Release Reaction / Fabris, F. / Cella, G. / Randi, M. / Casonato, A. / Fussi, F. / Girolami, A. -- Characterization of a New Potent Heparin / Bhargava, Akhil S. / Günzel, Peter -- Side Effects of Heparin / Weber, Ellen / Walter, Erhard / Harenberg, Job -- Role of Heparin-Like Molecules in Atherogenesis / Rosenberg, Robert D. / Castellot, John J. / Karnovsky, Morris J. -- Unresolved Problems in the Use of Heparin / Verstraete, Marc -- IV. Experience with "Monitoring of Heparin Therapy" -- Heparin Treatment of Deep Venous Thrombosis: Correlation Between Clinical Effects and Heparin Assays / Asbjørn Holm, Hans / Abildgaard, Ulrich -- Heparin-, Heparin Cofactor- and Platelet Factor 4 Plasma Levels Under Heparin Treatment / Bender, Norbert / Schlegel, Jürgen / Hach, Viola / Maximilian Kirchmaier, Carl / Breddin, Hans Klaus -- Determination of Heparin, Partial Thromboplastin Time and Antithrombin III after Subcutaneous Heparin Administration / Schöndorf, Theodor H. / Paplham, Helena / Franz, Klaus -- Monitoring of Heparin During Extracorporal Circulation in Open Heart Surgery / Spaethe, Reiner / Naumann, Margot -- Chromogenic and Fluorogenic Assays - A Challenge for Conventional Monitoring of Heparin Therapy? / Marbet, German A. / Duckert, François -- V. Concluding Discussion -- Introduction -- Subject Index