New Aspects of Storage and Release Mechanisms of Catecholamines

Welcome.- Opening Remarks.- Session 1 Origin and Axonal Transport of Adrenergic Nerve Granules.- Studies on the Origin of the Granulated and Non-granulated Vesicles.- The Effects of Drugs on Axonal Transport of Amine Storage Granules.- Invited Comment.- Session 2a Mechanism of Transmitter Release with Special Reference to the Problem of Exocytosis (I).- Opening Remarks.- Immunological Properties of Chromogranin.- Immunohistochemical Localization of Chromogranins in Sheep Sympathetic Neurons and their Release by Nerve Impulses.- Session 2b Mechanism of Transmitter Release with Special Reference to the Problem of Exocytosis (II).- Quantal Aspects of the Secretion of Catecholamines and Dopamine-?-hydroxylase from the Adrenal Medulla.- Some Aspects of the Quantal Release of the Adrenergic Transmitter.- Some Further Aspects on the Release of the Adrenergic Transmitter.- Quantal or Graded Secretion of Adrenal Medullary Hormone and Sympathetic Neurotransmitter.- Session 3 Chemical Sympathectomy.- Chemical Sympathectomy with 6-Hydroxydopamine.- Session 4a Effects of Drugs on Uptake and Release of Catecholamines (I).- Effect of Some Metabolic Factors and Drugs on Uptake and Release of Catecholamines in vitro and in vivo.- Saturation of the Uptake of Noradrenaline as a Determinant of Pharmacological Effects.- Cholinomimetic Drugs and Release of the Adrenergic Transmitter.- Session 4b Effects of Drugs on Uptake and Release of Catecholamines (II).- Membrane Effects of Catecholamine Releasing Drugs.- Effect of Angiotensin on Noradrenaline Release of the Isolated Rabbit Heart.- Neuronal and Hormonal Control of Tyrosine Hydroxylase and Phenylethanolamine N-methyltransferase Activity.- Session 4c Effects of Drugs on Uptake and Release of Catecholamines (III).- Effect of Drugs on AmineUptake Mechanisms in the Brain.- Release of Monoamines in the Central Nervous System.- The Effect of Different Neuroleptic Drugs on the Monoamine Neurons of the Rat Brain.- Release of Catecholamines from the Hypothalamus by Drugs and Electrical Stimulation.- Session 5.- General Discussion.- Author Index.