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| Artikel-Nr.: 5667A-9783642623615 Herst.-Nr.: 9783642623615 EAN/GTIN: 9783642623615 |
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| 1. An Introduction to Transcription Factors.- Mechanisms of Transcriptional Activation in Eukaryotes.- Multiple Mechanisms of Transcriptional Repression in Eukaryotes.- Genomic Approaches to the Study of Transcription Factors.- 2. Transcription Factors in Pathophysiology.- Biological Roles of the STAT Family in Cytokine Signaling.- Members of the T-Cell Factor Family of DNA-Binding Proteins and Their Roles in Tumorigenesis.- Transcription Factors in the Control of Tumor Development and Progression by TGF-? Signaling.- The p53 Transcription Factor as Ther apeutic Target in Cancer.- The Role of Ets Transcription Factors in Mediating Cellular Transformation.- Function of the E2F Transcription Factor Family During Normal and Pathological Growth.- c-Myc in Cellular Transformation and Cancer.- NF-?B: Critical Regulator of Inflammation and the Immune Response.- Hepatitis BVirus X Protein: Structure-Function Relationships and Role in Viral Pathogenesis.- Regulation of Xenobiot ic Detoxification by PXR, CAR, GR, VDR and SHP Receptors: Consequences in Physiology.- 3. Exogenous Control of Transcription Factor Activity.- Potential of Transcription Factor Decoy Oligonucleotides as Therapeutic Approach.- Selective Estrogen Receptor Modulators as Therapeutic Agents in Breast Cancer Treatment.- Artificial Zinc Finger Peptides: A Promising Tool in Biotechnology and Medicine.- Tetracycline-Controlled Transactivators and Their Potential Use in Gene Therapy Applications.- Modulating Transcript ion with Artificial Regulators. Weitere Informationen: | | Author: | Manfred Gossen; Jörg Kaufmann; Steven J. Triezenberg | Verlag: | Springer Berlin | Sprache: | eng |
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| Weitere Suchbegriffe: DNA; biotechnology; cellular transformation; eukaryote; gene therapy; genes; genomic biology; pathophysiology; physiology; transciption factor biology; zinc, DNA, biotechnology, cellular transformation, eukaryote, gene therapy, genes, genomic biology, pathophysiology, physiology, transciption factor biology |
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